• Adjunctive topical corticosteroids are often administered with UV-B phototherapy or oral psoralen plus UV-A (PUVA) photochemotherapy for the treatment of psoriasis. Five studies comparing PUVA alone with PUVA and topical corticosteroid preparations showed more rapid rates of clearing and a smaller total UV-A exposure with the latter regimen. However, one study demonstrated a higher relapse rate in association with corticosteroid use. Further studies to better define these risks are recommended. Six of seven reports evaluating the use of topical corticosteroid preparations with UV-B phototherapy failed to demonstrate an advantage to this regimen when compared with UV-B phototherapy alone. Therefore, the use of a topical corticosteroid preparation with UV-B phototherapy for the treatment of psoriasis is not recommended.
(Arch Dermatol. 1991;127:1708-1713)
Meola T, Soter NA, Lim HW. Are Topical Corticosteroids Useful Adjunctive Therapy for the Treatment of Psoriasis With Ultraviolet Radiation?A Review of the Literature. Arch Dermatol. 1991;127(11):1708-1713. doi:10.1001/archderm.1991.01680100108015