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January 1992

Goodman and Gillman's The Pharmacological Basis of Therapeutics

Author Affiliations

Boston, Mass


edited by Alfred Goodman, Theodore Roll, Alan Nies, and Palmer Taylor, 1811 pages, with black-and-white illus, Elmsford, NY, Pergamon Press Inc, 1990.

Arch Dermatol. 1992;128(1):132. doi:10.1001/archderm.1992.01680110146030

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


Goodman and Gillman's The Pharmacological Basis of Therapeutics has been a trusted resource for medical students and physicians for the past 50 years. This edition, the eighth, consists of 67 chapters contributed by 61 authors. The book is divided into 17 sections that cover general principles, organ-specific therapeutics, anti-inflammatory agents, anti-infectious agents, chemotherapy of neoplastic diseases, immunosuppression, vitamins, and toxicology. A brief, 20-page section on dermatology has been written by Mary Margaret Shren and David Viccars.

The basic format of Goodman and Gillman's The Pharmacological Basis of Therapeutics has not changed. The book begins with a thorough review of the general principles of pharmacology, including pharmacokinetics, mechanisms of action, and toxicology. The content, however, has been significantly updated to include recently acquired experimental information. As an example, this edition has a well-written review of transmembrane signaling mechanisms, including G proteins and the protein kinases. The information on organspecific and disease-specific drugs has

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