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The series Methods in Enzymology is highly respected for its in-depth presentation of up-to-date methodologies in important specialty subjects. Virtually all college and science-oriented libraries subscribe to this series, which makes the two volumes reviewed here accessible to most readers. Because of the price, few individuals will purchase the books, but the major recent discoveries of the nuclear receptors gives perfect timing to the publication of these two volumes. Having said this, I must add that the publishers appear to have unnecessarily padded the text to stretch it into two volumes, knowing that they have a captive consumer in libraries.
Volume 189 (part A) deals with the molecular and metabolic aspects of retinoids. The three first chapters, dealing with structure of retinoids, could have been combined into a single chapter while preserving the excellent and informative tables. The redundancy is particularly egregious in the 11 (!) chapters dealing with high-performance liquid
Blumenburg M. Methods in Enzymology. Arch Dermatol. 1992;128(6):870. doi:10.1001/archderm.1992.01680160160035