To the Editor.
—The pathomechanism of epidermoid cysts is still not fully understood. Previously, we1 mentioned the possible role of human papillomavirus (HPV) in the genesis of plantar epidermoid cysts. The HPV-related plantar cysts had particular histologic features, ie, intracytoplasmic eosinophilic bodies in the wall and vacuolar structures in the cavity. In this study, we investigated for the presence of HPV in palmar epidermoid cysts, which are thought to have the same pathomechanism as plantar epidermoid cysts.
Materials and Methods
.—Within a 3-year period, we observed 15 patients with palmar epidermoid cysts. There were 12 male and three female patients, ranging in age from 14 to 79 years (mean, 43 years). The cysts were distributed on the palm (nine cases) and the palmar (three cases) and lateral (three cases) sides of the fingers (Fig 1). Two patients had a history of preceding trauma at the site where the cysts developed.
Egawa K, Inaba Y, Honda Y, Johno M, Ono T. 'Cystic Papilloma': Human Papillomavirus in a Palmar Epidermoid Cyst. Arch Dermatol. 1992;128(12):1658-1659. doi:10.1001/archderm.1992.04530010094027