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Article
September 1993

Radiation Therapy of Giant Aggressive Keratoacanthomas

Author Affiliations

From the Department of Dermatology, University of Pennsylvania Medical School, Philadelphia.

Arch Dermatol. 1993;129(9):1162-1165. doi:10.1001/archderm.1993.01680300090014
Abstract

Background and Design:  Giant aggressive keratoacanthoma is a rare destructive subset of keratoacanthoma that frequently involves the facial region, grows rapidly to a large size, and often recurs after surgical management. The effectiveness of ionizing radiation therapy was examined in a retrospective study involving 16 patients; 14 of the tumors had recurred after surgical therapy.

Results:  All tumors resolved with satisfactory cosmetic results and without recurrence following a fractionated course of superficial radiation therapy.

Conclusions:  Radiation therapy is an effective therapeutic modality for giant aggressive keratoacanthomas.(Arch Dermatol. 1993;129:1162-1165)

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