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October 1993

Sporotrichosislike Infection Caused by Mycobacterium avium in the Acquired Immunodeficiency Syndrome

Author Affiliations

Unité d'Immunopathologie Hôpital Broussais 96, rue Didot 75014 Paris, France; Service de Microbiologie Hôpital Broussais 96, rue Didot 75014 Paris, France

Arch Dermatol. 1993;129(10):1343-1344. doi:10.1001/archderm.1993.01680310115026

Cutaneous manifestations are infrequent in the course of Mycobacterium avium infections. We report a case of sporotrichosislike skin lesions caused by M avium in a patient with the acquired immunodeficiency syndrome (AIDS).

Report of a Case.  A 50-year-old homosexual man from the French Caribbean was admitted to our institution for weight loss, fever, and progressive malaise. Esophageal candidiasis and human immunodeficiency virus infection were diagnosed. The CD4 cell count was 0.06×109/L. The patient was treated with fluconazole (100 mg/d); zidovudine therapy was begun. Despite the treatment, constitutional symptoms did not improve: after 4 weeks, the patient noted the occurrence of subcutaneous abscesses in the right wrist. The lesions were indurated and intermittently drained a fluid. Within 2 weeks, the lesions spread to involve the forearm and the arm in a sporotrichoid fashion. Direct examination of the pus showed the presence of numerous acid-fast organisms, identified on culture as M avium. Cultures of sputum,

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