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Article
December 1993

A Progressive Asymptomatic Hyperpigmented Papular Eruption

Arch Dermatol. 1993;129(12):1607-1612. doi:10.1001/archderm.1993.04540010088014
Abstract

DIAGNOSIS:  Confluent and reticulated papillomatosis (CRP) of Gougerot and Carteaud.

CLINICAL COURSE  One week after the biopsy specimen was obtained, the patient's lithium dose was lowered to 1200 mg/d by her psychiatrist. Shortly thereafter gradual resolution of the eruption was noted. No other therapy had been instituted. Reexamination at 3 weeks revealed a significant degree of resolution; after 2 months, only a faint residual macular hyperpigmentation remained.

DISCUSSION  [ill] is controversial. The possibility that CRP may be associated with endocrinopathies has also been reported, but the majority of cases are not associated with any endocrine abnormalities.8,9Several authors have suggested that CRP may be a variant of pseudo-acanthosis nigricans.10,11 Kesten and James12 raised the possibility that pseudoathrophoderma colli, a rare pigmentary dermatosis that occurs predominantly on the neck and thorax of women, may be an early form of CRP. Groh and Schnyder13 stated that CRP may be a variant of cutaneous amyloidosis; they described three patients with

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