The report by Nelson et al1 provides an important observation on basaloid follicular hamartoma, but the authors failed to address specifically the most problematic differential diagnosis, namely infundibulocytic basal cell carcinoma.2 Illustrating this dilemma are photomicrographs taken from two recent publications on these subjects: the Figure, top, shows a solitary basaloid follicular hamartoma as reported by Brownstein3; the Figure, bottom, is an infundibulocytic basal cell carcinoma as pictured by Burgdorf and Koester (provided by A. B. Ackerman, MD).4 The lesions appear virtually identical. Do Dr Nelson and colleagues be Top, A solitary basaloid follicular hamartoma as illustrated by Brownstein's3 figure 6. Bottom, An infundibulocytic basal cell carcinoma as illustrated by Burgdorf and Koester's4 Figure 5. lieve that some infundibulocytic basal cell carcinomas are in fact basaloid follicular hamartomas, or vice versa?
White WL, Abernethy JL. Other Questions on Basaloid Follicular Hamartoma. Arch Dermatol. 1994;130(2):254-255. doi:10.1001/archderm.1994.01690020124024