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April 1994

Treatment of Squamous Cell Carcinoma of the Lip in a Kidney Transplant Patient

Author Affiliations

University of Navarra, Pamplona, Spain

Arch Dermatol. 1994;130(4):428-430. doi:10.1001/archderm.1994.01690040032004

REPORT OF A CASE  A 47-year-old male office worker underwent a kidney transplantation in February 1985 for terminal chronic renal insufficiency of unknown origin. From that time until December 1990, he continued immunosuppressive treatment with azathioprine (150 mg/d) and prednisone (10 mg/d). Since January 1991, he has received azathioprine (75 mg/d), cyclosporine (1.1 mL every 12 hours), and prednisone (10 mg/d).In March 1992, the patient presented at our dermatology surgery unit with an ulcerous 1-cm lesion located on the lower lip (Figure 1). The lesion had been developing for about 1 month. Findings from his physical examination revealed no palpable adenopathies in the main ganglionic chains of the head and neck. A computed tomographic scan of the neck showed no relevant morphologic alterations. An incisional biopsy specimen confirmed the clinical suspicion of squamous cell carcinoma (SCC). Histologically, 50% of the cells were seen to be atypical, with a minimal

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