Hereditary woolly hair has occasionally been associated with abnormalities of the skin,1 eyes, and ears. Barker et al2 have recently reported seven families in Greece affected by a new autosomal recessive syndrome characterized by the asso- ciation of woolly hair, palmoplantar keratoderma, and cardiac abnormalities.2
We describe two members of a family who presented a similar, but not identical, condition.
Report of Cases.
Case 1. A 20-year-old electrician was admitted to our clinic in June 1991 for a palmoplantar keratoderma. His history revealed that the plantar keratoderma had been present since the age of 1 year and had progressively worsened during the years. Palmar hyperkeratosis first appeared at the age of 17, when the patient started his job as an electrician.The clinical examination revealed a very thick, yellow hyperkeratosis over the pressure areas of the patient's palms and soles (Figure 1). Painful hyperkeratotic lesions of the
Tosti A, Misciali C, Piraccini BM, Fanti PA, Barbareschi M, Ferretti RM. Woolly Hair, Palmoplantar Keratoderma, and Cardiac Abnormalities: Report of a Family. Arch Dermatol. 1994;130(4):522-524. doi:10.1001/archderm.1994.01690040130027