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May 1994

Clinical Manifestations of Photosensitivity in Patients With Human Immunodeficiency Virus Infection

Author Affiliations

Columbia-Presbyterian Medical Center 29 Jones Ave Chatham, NY 12037; New York, NY

Arch Dermatol. 1994;130(5):630-633. doi:10.1001/archderm.1994.01690050098018

The CLINICAL SPECTRUM of human immunodeficiency virus (HIV) disease involving skin is broad and varied. It includes localized and generalized inflammatory processes, cutaneous and systemic infections, and malignancies.1 One interesting phenomenon that appears to occur in some patients with HIV infection is hypersensitivity to UV light resulting in a number of very different types of cutaneous diseases. With the recent articles on possible acceleration of HIV disease by UV light exposure,2-5 it would appear important for clinicians and scientists to explore and explain the role of solar radiation in HIV infection. Porphyria cutanea tarda (PCT)6-8 and photosensitive granuloma annulare (GA)9,10 are known to occur with HIV. With the article by Berger and Dahr on lichenoid photoeruptions in this issue of the Archives,11 along with our own experience at Columbia-Presbyterian Medical Center in New York City, several other presentations of HIV photosensitivity can be added. These

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