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June 1994

Enhancement of PUVA Phototoxic Effects Following Celery Ingestion: Cool Broth Also Can Burn

Author Affiliations

Department of Dermatology Hospital de la Santa Creu i Sant Pau Universitat Autònoma de Barcelona Avda San Antonio M Claret 167 08025 Barcelona, Spain

Arch Dermatol. 1994;130(6):809-810. doi:10.1001/archderm.1994.01690060147031

Severe phototoxic burn following celery ingestion was first reported in a 65-year-old woman who visited her suntan parlor 1 hour after the ingestion of 450 g of celery.1 We describe a similar reaction in a patient receiving photochemotherapy.

Report of a Case.  A 53-year-old woman, skin type IV, had relapsing generalized eruptive lichen planus, confirmed by biopsy, since 1987. She had been treated with four courses of oral prednisone (30 mg/d) for 15 days and photochemotherapy for 3 months, leading to clearance with no untoward effects. In July 1991, another relapse of her skin disease prompted a new course of treatment with methoxypsoralen (Oxsoralen, Galderma SA, Madrid, Spain), 40 mg/d (0.6 mg/kg per day), taken with breakfast 2 hours before the irradiation, twice a week. Twelve hours after the eighth PUVA session, a typical PUVA burn developed, with dusky red erythema, stinging, and burning on the exposed areas. No

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