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Article
October 1994

Erythropoietic Protoporphyria and Lupus Erythematosus: Case Report and Review of the Literature

Author Affiliations

Department of Dermatology University of Cincinnati Medical Center 234 Goodman St, Pavilion A-3 Cincinnati, OH 45267-0523

Arch Dermatol. 1994;130(10):1330-1332. doi:10.1001/archderm.1994.01690100120026
Abstract

Various forms of porphyria1 have been reported in association with lupus erythematosus (LE). Although the nature of the association is unclear, it has been proposed that it is not coincidental. No reports of erythropoietic protoporphyria in association with LE have been published. We describe a young man with both diseases.

Report of a Case.  A 34-year-old white man developed two asymptomatic plaques on his forehead 1 month before presentation. In addition, he described a lifelong history of intolerance to sunlight. He reported that following 20 to 60 minutes of sun exposure, burning and stinging of the sun-exposed skin developed in association with erythema and edema, which persisted for 1 to 2 days. He also noted the slow appearance of scarlike lesions over his hands and forearms. A sister and two brothers have similar sensitivity to sunlight.Examination of the skin revealed two round, welldefined, slightly infiltrated, smooth-surfaced, finescale, erythematous

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