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October 1994

Clinical Dermatology

Author Affiliations

Boston, Mass

Arch Dermatol. 1994;130(10):1339. doi:10.1001/archderm.1994.01690100129028

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


Oxidative Stress in Dermatology deals with some of the roles reactive oxygen species (ROS) play in the pathophysiology of skin diseases and is edited by two people currently working in this field.

The biology of free radicals, including ROS, is a newly emerging field of interest. Free radicals, and possibly other reactive species, are implicated in over 100 conditions, including myocardial and various neurologic diseases, as well as some dermatologic conditions, the latter being the focus of this book. Oxidative stress is defined as the state occurring when the formation of ROS and the defenses against these species are not in balance.

The book is divided into three sections. The first, entitled ''Oxidants, Antioxidants, and Oxidative Injury in Dermatopathology'' (chapters 1 through 15), covers the basic principles of the field as well as the various types of injury ROS can cause in skin. Chapter 1 defines the subject, describes the

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