Baalbaki et al1 reported the temporal response of confluent and reticulated papillomatosis to etretinate (0.25 to 0.4 mg/kg per day for 1 month) in five adult men who had been previously treated with ketoconazole without success. No mention was made in their article about minocycline treatment,2,3 which is a therapeutic alternative possibly safer than ketoconazole and etretinate as regards potential hepatotoxicity and teratogenicity in women of child-bearing age. This prompts us to report a case of confluent papillomatosis in a young woman who responded to minocycline treatment.
Report of a Case.
A 20-year-old white woman presented with a hyperpigmented reticulated eruption that had appeared 5 years before, had extended slowly, and had remained stable for the last 2 years. Apart from minimal atopic dermatitis, her medical history was unremarkable. She denied intake of any oral medication or drug abuse. Physical examination disclosed hyperpigmented nondesquamative reticulated macules on the
Puig L, de Moragas JM. Confluent and Reticulated Papillomatosis of Gougerot and Carteaud: Minocycline Deserves Trial Before Etretinate. Arch Dermatol. 1995;131(1):109-110. doi:10.1001/archderm.1995.01690130113028