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January 1995

Confluent and Reticulated Papillomatosis of Gougerot and Carteaud: Minocycline Deserves Trial Before Etretinate

Arch Dermatol. 1995;131(1):109-110. doi:10.1001/archderm.1995.01690130113028

Baalbaki et al1 reported the temporal response of confluent and reticulated papillomatosis to etretinate (0.25 to 0.4 mg/kg per day for 1 month) in five adult men who had been previously treated with ketoconazole without success. No mention was made in their article about minocycline treatment,2,3 which is a therapeutic alternative possibly safer than ketoconazole and etretinate as regards potential hepatotoxicity and teratogenicity in women of child-bearing age. This prompts us to report a case of confluent papillomatosis in a young woman who responded to minocycline treatment.

Report of a Case.  A 20-year-old white woman presented with a hyperpigmented reticulated eruption that had appeared 5 years before, had extended slowly, and had remained stable for the last 2 years. Apart from minimal atopic dermatitis, her medical history was unremarkable. She denied intake of any oral medication or drug abuse. Physical examination disclosed hyperpigmented nondesquamative reticulated macules on the

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