This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.
We appreciate the comments by Dr Cerroni concerning our article; we know of his expertise in the field of immunophenotyping of cutaneous lymphoproliferative disorders. The expression of some T-cell—associated antigens by B lymphocytes is a frequent and useful criterion to identify some B lymphocytes, both in frozen and in paraffin-embedded sections.
Let us supply some further histologic data. Our immunohistochemical studies were performed on paraffinembedded sections with the following antibodies: Mtl, UCHL1, L26, MB-2, and antiκ and antiλ light chains. More than 90% of lymphoid cells were positive for anti—T-cell antibodies (MT1 and UCHL1); less than 10% were positive forantiB-cell antibodies (126 and MB-2). Normal-appearing plasma cells, containing both κ and λ light chains, were scattered throughout the infiltrate, mainly in the periphery of the nodules. Histiocytic cells, not reactive with the above= mentioned antibodies, formed eccentrically situated groups within the nodules.
These data, and those previously mentioned, prompt us
Roo E, Villegas C, Lopez-Bran E, Jimenez E, Valle P, Sanchez-Yus E. Pseudolymphoma?-Reply. Arch Dermatol. 1995;131(2):226. doi:10.1001/archderm.1995.01690140112022