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March 1995

Anetoderma May Reveal Cutaneous Plasmacytoma and Benign Cutaneous Lymphoid Hyperplasia

Author Affiliations

Department of Dermatology Hôpital Henri Mondor 94010 Créteil Cedex, France


Arch Dermatol. 1995;131(3):365-366. doi:10.1001/archderm.1995.01690150131036

We report two cases in which anetoderma was associated with a plasma cell infiltrate, revealing a primary cutaneous plasmacytoma in one case and a benign cutaneous lymphoid hyperplasia in the other.

Report of Cases.Case 1.  A 64-year-old man presented with a 3-year history of increasingly numerous well-circumscribed areas of slack skin on the trunk and upper arms (Figure 1). Some anetodermic lesions developed at the site of initially inflammatory papulonodular lesions.Ten years before, a diagnosis of primary Sjögren's syndrome had been made. Skin biopsy specimens were obtained on infiltrated plaques and on anetodermic lesions. A dense plasma cell infiltrate was found in all lesions. This infiltrate was predominantly peripilar

Figure 1.  Anetoderma on the flank. and was composed of large-sized plasma cells sometimes showing atypical nuclei (Figure 2). On anetodermic lesions, a dermal atrophy with focal loss of normal elastic fibers was demonstrated by orcein staining.The IgG-κ

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