We report two cases in which anetoderma was associated with a plasma cell infiltrate, revealing a primary cutaneous plasmacytoma in one case and a benign cutaneous lymphoid hyperplasia in the other.
Report of Cases.Case 1.
A 64-year-old man presented with a 3-year history of increasingly numerous well-circumscribed areas of slack skin on the trunk and upper arms (Figure 1). Some anetodermic lesions developed at the site of initially inflammatory papulonodular lesions.Ten years before, a diagnosis of primary Sjögren's syndrome had been made. Skin biopsy specimens were obtained on infiltrated plaques and on anetodermic lesions. A dense plasma cell infiltrate was found in all lesions. This infiltrate was predominantly peripilar
Anetoderma on the flank. and was composed of large-sized plasma cells sometimes showing atypical nuclei (Figure 2). On anetodermic lesions, a dermal atrophy with focal loss of normal elastic fibers was demonstrated by orcein staining.The IgG-κ
Jubert C, France C, Cosnes A, Wechsler J, Andre P, Revuz J, Bagot M. Anetoderma May Reveal Cutaneous Plasmacytoma and Benign Cutaneous Lymphoid Hyperplasia. Arch Dermatol. 1995;131(3):365-366. doi:10.1001/archderm.1995.01690150131036