REPORT OF A CASE
A 19-month-old Albanian girl developed yellow-red papules in both eyelids at age 6 months. Over the past year, new lesions developed on her head and upper trunk. She was asymptomatic and otherwise healthy.The examination revealed multiple scattered 2- to 3-mm yellow-red papules over the scalp and face (Figure 1). A few were present on her upper chest. A complete blood cell count, serum protein electrophoresis, and chemistry panels were normal. Bone marrow aspirate, skeletal survey, chest radiograph, and computed tomographic scan were normal.Histologic findings from a typical lesion are shown (Figure 2). Special stains for CD1 and S100 were positive in a few dermal cells; HLA-DR was strongly positive. Electron microscopy was performed (Figure 3 and Figure 4).What is your diagnosis?
Benign cephalic histiocytosis.
The epidermis was slightly atrophic. The dermis contained large histiocytic cells with ground-glass cytoplasm, a few multinucleated giant cells,
Baler JS, DiGregorio FM, Hashimoto K. Facial Papules in a Child. Arch Dermatol. 1995;131(5):613-614. doi:10.1001/archderm.1995.01690170115020