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July 1995

Hepatitis C Virus Infection in Patients With Porphyria Cutanea Tarda Evaluated in New York, NY

Author Affiliations

Photomedicine Section

Department of Dermatology New York University School of Medicine New York, NY 10016

Arch Dermatol. 1995;131(7):849. doi:10.1001/archderm.1995.01690190105023

Previous reports have indicated a high prevalence of hepatitis C virus infection in patients with sporadic porphyria cutanea tarda (PCT) seen in Europe and Ireland.1,2 Since the prevalence of hepatitis C virus infection in patients seen in the United States has not been reported, the hepatitis C antibody status of patients with PCT who underwent follow-up in the photomedicine Section of our institution from July 1992 through June 1994 was assessed.

Patients and Methods.  During the study period, a total of six patients with sporadic, nonfamilial PCT underwent followup in the Photomedicine Section. Four patients had chronic hepatitis screening tests performed; despite repeated counseling, the other two declined due to cost of the tests. The profile of these four patients and the results of the hepatitis screening are shown in the Table. Hepatitis C antibody detection was conducted by enzyme-linked immunosorbent assay with the exception of case 3, where

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