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The patient was a man aged forty years, who about three years ago developed an epithelioma of the lower lip which was removed by some kind of caustic application. About a year later recurrence took place in the cervical glands, and when he came under Dr. Lewis's observation about a month ago the disease had progressed to such an extent that a radical operation was impossible. It was then decided to try the effect of the erysipelas toxines. Gibier's preparation, known as the double toxines of erysipelas, was first employed, and afterward the new preparation made by Dr. Coley. At the point of each injection an abscess forms, which softens and discharges, and in this way the epithelioma is gradually being reduced in size.
Dr. H. G. Piffard said that in one case of supposed malignant disease where he was consulted as to the advisability of employing the toxine treatment,
LEWIS D. A Case of Epithelioma treated by means of Injections of the Toxines of Erysipelas. Arch Dermatol. 1996;132(6):618. doi:10.1001/archderm.1996.03890300030005