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June 1996

Vascular Papules on the Dorsum of the Hands

Author Affiliations

Massachusetts General Hospital and Harvard Medical School, Boston

Arch Dermatol. 1996;132(6):703-704. doi:10.1001/archderm.1996.03890300131019

REPORT OF A CASE  A woman presented with multiple, grouped, red-brown papules and nodules on the dorsum of her left hand (Figure 1). The lesions ranged in size from 2 to 4 mm in diameter and had been present for several years.A biopsy specimen showed a vascular proliferation with numerous giant cells (Figure 2 and Figure 3).What is your diagnosis?

DIAGNOSIS:  Multinucleate cell angiohistiocytoma (MCAH).

DISCUSSION  The MCAH is a benign vascular proliferation that was originally described in abstract form in 1985.1 Since then, only 20 cases have been reported, most of them in the European literature.1-4 Only very recently has a review of several cases been reported in the United States.5 The MCAH may be underrecognized and probably occurs more frequently than is reflected by the existing literature.The MCAH has distinctive clinical and pathologic features. It most commonly affects middle-aged women,

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