I read the excellent review and case report by Walsh et al1 that appeared in the December 1995 issue of the Archives relating to the impressive hair regrowth observed in a single subject with male pattern androgenetic alopecia. The authors also informed us that human trials using combinations of finasteride and minoxidil in androgenetic alopecia "are currently underway." I was surprised, however, that the authors had sufficient comfort at this time to recommend that "this regimen should be considered for the treatment of patients with mild to moderate androgenetic alopecia who desire medical therapy following informed consent."
The authors describe the use of this regimen in a 32-year-old healthy white man with androgenetic alopecia. The regimen consists of a combination of topical solutions of minoxidil and tretinoin (final solution, 3% minoxidil and 0.01% tretinoin, with 1 mL applied twice daily to the balding scalp) combined with the
Rand S. Hair Growth Therapy(ies) for Androgenetic Alopecia. Arch Dermatol. 1996;132(6):714-715. doi:10.1001/archderm.1996.03890300144029