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July 1996

Pulsed Dye Laser-Resistant Port-wine Stains

Author Affiliations

Boston, Mass

Stanford, Calif

San Diego, Calif

London, England

Department of Dermatology Harvard Medical School Division of Dermatology New England Deaconess Hospital 110 Francis St, 7H Boston, MA 02215

Arch Dermatol. 1996;132(7):839-841. doi:10.1001/archderm.1996.03890310131028

Port-wine stains (PWSs) are congenital lesions characterized by ectatic vessels in the superficial dermis. The cause of these lesions is unknown, but 1 theory is that they result from a diminished neural regulation of the blood flow, secondary to a reduced number of perivascular nerves,1 which, in turn, results in erythrostasis and progressive vessel ectasia. The use of pulsed dye lasers is currently the treatment of choice for PWSs. The 577-nm or 585-nm wavelength selectively targets oxyhemoglobin and the 450-microsecond pulse duration is sufficient to cause intravascular coagulation without excessive heat dissipation to the epidermis or adjacent dermal structures.

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