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August 1996

Classification of Cutaneous Lymphomas

Author Affiliations

Department of Histopathology Rotherham Hospital NHS Trust Rotherham S60 2UD, England

Arch Dermatol. 1996;132(8):972-973. doi:10.1001/archderm.1996.03890320122023

Willemze and the Dutch group1 must be congratulated on their new proposed classification of primary cutaneous T-cell lymphomas, based primarily on CD30 expression as a prognostic factor. It is debatable, however, as to whether all cases of lymphomatoid papulosis justify the designation lymphoma and whether Sézary syndrome is best classified as low-grade cutaneous T-cell lymphoma, on the basis of clinical behavior and prognosis.

Their concepts regarding the classification of cutaneous B-cell lymphoma (CBCL), however, are contrary to alternative views held in countries such as the United Kingdom and Italy.2 Furthermore, they are not consistent with those expressed in a recent Archives editorial.3

The newly proposed classification of lymphoid neoplasms by the International Lymphoma Study Group4 gives full recognition to the existence of extranodal marginal zone B-cell lymphoma (of mucosa-associated lymphoid tissue type) as a distinct clinicopathologic entity. Also, immunocytoma (lymphoplasmacytoid lymphoma) is now regarded as a

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