In 1990, Harms et al1 described a new clinical entity that they descriptively defined as "papular-purpuric 'gloves and socks' syndrome" (PPGSS). These authors, on the basis of a careful review of the literature, concluded that PPGSS had never been described. After the first 5 patients reported by Harms et al,1 another 20 cases were published.1-17 One of these patients was seen in June 1993 at our institute.13
The recent discovery of 2 other cases has prompted us to present the results of a clinical and immunovirological study.
Report of Cases. Case 1.
A 39-year-old man was admitted because of a rash that was accompanied by a headache and localized exclusively to the hands and feet. The history was negative for intake of drugs. The rash was characterized by edema on which erythematopapular-purpuric lesions had developed: they were round, a few millimeters in diameter, slightly raised and
Veraldi S, Rizzitelli G, Scarabelli G, Gelmetti C. Papular-Purpuric 'Gloves and Socks' Syndrome. Arch Dermatol. 1996;132(8):975-977. doi:10.1001/archderm.1996.03890320125026