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October 1996

Hepatitis C Virus in Dermatology

Author Affiliations

University of California, Davis, Medical School University of California, San Francisco, Medical School 400 Parnassus San Francisco, CA 94143-0132

Arch Dermatol. 1996;132(10):1247. doi:10.1001/archderm.1996.03890340113021

Pawlotsky et al,1 in an otherwise in-depth and complete review of the dermatologic manifestations of hepatitis in the October 1995 issue of the Archives, failed to cite pruritus as a symptom of hepatitis C as described by myself and Teresa Wright.2 This association was confirmed by the article of Kanazawa et al.3

Recognizing pruritus as a manifestation of hepatitis C is important for 2 reasons. First, pruritus may be the presenting sign of hepatitis C, and therefore it should be a consideration in the diagnostic evaluation of any patient suffering from pruritus not secondary to a primary skin disorder. Second, the pruritus, which may vary in intensity from mild to disabling severity, may be the patient's primary manifestation of hepatitis C and may be effectively alleviated by prudent therapeutic intervention. Since publication of my article, I have treated an additional patient with severe pruritus and hepatitis C

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