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November 1996

Eradication of Helicobacter pylori as the Only Successful Treatment in Rosacea

Author Affiliations

Postgraduate Medical Institute Ruzinov Hospital Ruzinovska 6 826 06 Bratislava, Slovakia


Arch Dermatol. 1996;132(11):1393. doi:10.1001/archderm.1996.03890350137032

We observed a patient with typical rosacea, microscopically positive for Demodex folliculorum (Figure 1), who was previously unsuccessfully treated with general and local treatment, and who improved after our therapy, which eradicated Helicobacter pylori.

Report of a Case.  A 53-year-old white woman with rosacea was previously treated for 9 years with antibiotics (tetracycline hydrochloride, deoxycycline, and amoxicillin), retinoids (isotretinoin), and with local treatment, which included ichthammol, sulfur, corticosteroids (1% halcinonide and 1% mometasone furoate), and the antibiotic clindamycin.In spring 1994 the patient's local finding dramatically worsened (Figure 2) and she was admitted to our department. She complained of a history of intermittent gastric pain and diarrhea. When she was 16 years old she overcame hepatitis A. A gastrofibroscopical examination, which was performed in 1990, revealed chronic antrum gastritis. The presence of Helicobacter pylori was proven in a urease test, microscopically, and by culture. Treatment with metronidazole hydrochloride, amoxicillin,

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