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February 1997

Mucormycosis in a Patient With Acquired Immunodeficiency Syndrome

Author Affiliations

Department of Dermatology 2 Rhoads Pavilion Hospital of the University of Pennsylvania 3600 Spruce St Philadelphia, PA 19104


Birmingham, Ala

Arch Dermatol. 1997;133(2):249-251. doi:10.1001/archderm.1997.03890380123029

Mucormycosis classically affects patients who are immunocompromised or debilitated, including those with diabetes, malignant neoplasm, renal failure, and neutropenia.1 Despite the opportunistic nature of mucormycosis infection, there are few cases of cutaneous manifestations of the infection reported in patients with the acquired immunodeficiency syndrome (AIDS).2-5 We describe a patient with AIDS, neutropenia, and iron overload who developed primary cutaneous mucormycosis. In addition, the patient had recently undergone intralesional chemotherapy and radiation treatments on his face for Kaposi sarcoma.

Report of a Case.  A 41-year-old white man with AIDS manifested by a CD4 cell count below 10×109/L and a medical history that included disseminated Kaposi sarcoma, cytomegalovirus retinitis, recurrent herpes simplex infection, anemia, and adrenal insufficiency was admitted to the hospital with acute onset of right-sided facial pain and swelling. His facial Kaposi sarcoma had been treated previously with intralesional doxorubicin hydrochloride and radiation.On

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