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April 1997

Transient Cephalic Neonatal Pustulosis-Reply

Author Affiliations

Unité de Dermatologie Pédiatrique Hôpital Pellegrin-Enfants Place Amelie Raba Leon 33076 Bordeaux, France


Arch Dermatol. 1997;133(4):529-530. doi:10.1001/archderm.1997.03890400134025

In reply  The 2 patients described by Bardazzi et al are indeed closely related to the entity we described as neonatal Malassezia furfur pustulosis. We accept the contention that this disorder is spontaneously healing and that imidazole cream may just hasten its course. But it remains to be proven that such compounds act only as anti-inflammatory drugs in this context. On the contrary, we feel that the absence of yeasts of the genus Malassezia in smears or cultures may be related to the difficulty of obtaining adequate samples from such young infants. A definitive answer would be to perform biopsies, but the self-healing nature of this disorder and its mostly facial distribution render this procedure questionable on ethical grounds. We emphasize the need to sample pustules and to obtain a good-quality smear for direct examination and culture on Dixon or related appropriate media.Further studies are obviously needed to

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