REPORT OF A CASE
A 28-year-old white man came to us for removal of a warty plaque on his left palm. The lesion had been present as long as he could remember and had not changed. The patient had no significant medical or family history and was taking no medicines.A complete skin examination revealed a soft, fibrous, cerebriform plaque over the left lateral hypothenar eminence (Figure 1). A punch biopsy specimen showed a dome-shaped piece of skin with thick and vertically oriented collagen bundles (Figure 2).What is your diagnosis?
Isolated cerebriform collagenoma.
Focal acral hyperkatosis, acrokeratoelastoidosis, shagreen patch, degenerative collagenous plaques of the hands, and tumefactive amyloidosis are included in the differential diagnosis of isolated cerebriform collagenoma. Focal acral hyperkeratosis, which is a variant of acrokeratoelastoidosis, was originally described by Dowd et al1 in 1983. It usually occurs on the palms and is seen
Jones MS, Helm KF. A Solitary Warty Plaque. Arch Dermatol. 1997;133(7):911-912. doi:10.1001/archderm.1997.03890430131020