I read with interest in a recent issue of the Archives the "Off-Center Fold" case report by Evans et al1 of an asymptomatic scaly plaque measuring 1.1×1.5 cm, which showed histological features of mycosis fungoides (MF) and was interpreted as an example of unilesional MF.
Mycosis fungoides has received a great deal of public exposure in Australia with the death of Paul Eddington, the British actor, and more recently the public struggle of a patient with advanced MF who elected to undergo voluntary euthanasia under the recent controversial legislation passed in the Australian Northern Territory. The public perception of MF is that of a terminal disease.
I recall being sent for review the histopathologic material of 3 patients who underwent excision biopsies of solitary lesions measuring 1 to 2 cm in diameter that were associated with a short history of change and pruritus. While the histopathologic material on the
Kossard S. Unilesional Mycosis Fungoides or Lymphomatoid Keratosis?. Arch Dermatol. 1997;133(10):1312-1313. doi:10.1001/archderm.1997.03890460138022