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Vignette
October 2007

Intractable Wounds From a Herpes Simplex Infection in an Immunosuppressed Patient With Rheumatoid Arthritis

Arch Dermatol. 2007;143(10):1331-1344. doi:10.1001/archderm.143.10.1340

Herpes simplex virus (HSV) infections, characterized by painful grouped vesicles with erythema occurring on perioral and/or pubic areas, affect over 40 million people in the United States,1 where 1.6 million people are infected annually with HSV-2.2 The diagnosis of HSV is generally easy, but it becomes difficult in immunosuppressed populations.3

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