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October 2007

Nodular Lesions on the Arm—Diagnosis

Author Affiliations
 

MICHAEL E.MINGMD, MSCECARRIE ANN R.CUSACKMDSENAIT W.DYSONMDJACQUELINE M.JUNKINS-HOPKINSMDVINCENTLIUMDKARLA S.ROSENMANMD

Arch Dermatol. 2007;143(10):1323-1328. doi:10.1001/archderm.143.10.1323-g

The lesional biopsy specimen revealed numerous and diffuse inflammatory granulomas in the dermis. The granulomas were composed of histiocytes and giant cells containing numerous phagocytosed thick-walled cells. An asteroid body was also seen. The GMS stain showed the typical yeasts of lobomycosis in chains of uniform round to oval cells.

The nodules were completely excised, and the patient was given itraconazole, 200 mg/d, for 6 months as an attempt to prevent disease relapse.

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