Copyright 2007 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2007
A 45-year-old woman with stage IA nodular sclerosing Hodgkin lymphoma began a regimen of doxorubicin, bleomycin, vinblastine, and dacarbazine chemotherapy. Seventy-two hours later, she developed intensely itchy, erythematous, linear lesions affecting the arms, back, neck, occipital scalp, and hands. She was prescribed clobetasone propionate ointment, 0.05%, twice daily (Dermovate; GlaxoSmithKline, Brentford, Middlesex, England) because the pruritic eruption was suggestive clinically of a lichenoid dermatitis, and the rash subsided following the completion of the first course of chemotherapy.
Arseculeratne G, Berroeta L, Meiklejohn D, Mountain RE, Ryan JC, Spinou C, Das SN, Evans AT, Lowe JG. Bleomycin-Induced “Flagellate Dermatitis”. Arch Dermatol. 2007;143(11):1447-1462. doi:10.1001/archderm.143.11.1461