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March> 1, 2008

Solitary Nodule in a 3-Month-Old Male Infant—Diagnosis

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Copyright 2008 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2008

Arch Dermatol. 2008;144(3):405-410. doi:10.1001/archderm.144.3.dof70020-g

Findings from histologic examination showed whorls and fascicles of smooth muscle, as well as spindle-shaped myofibroblastic cells in a fibrous stroma. Additional round to oval cells were present with surrounding vascular channels, resembling the hemangiopericytoma pattern characteristic of these tumors. A trichrome stain confirmed the presence of smooth muscle, and an actin stain showed strong positivity. Further evaluation of the infant confirmed the solitary nature of the lesion. The patient was referred to the plastic surgery department for conservative excision of the lesion owing to its rapid growth rate.