MICHAEL E.MINGMD, MSCE
CARRIE ANN R.CUSACKMDSENAIT W.DYSONMDJACQUELINE M.JUNKINS-HOPKINSMDVINCENTLIUMDKARLA S.ROSENMANMD
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A 67-year-old man recently diagnosed as having Waldenström macroglobulinemia (WM) presented with an asymptomatic cutaneous eruption on his shins, ankles, and feet for several days. The diagnosis of WM was based on findings from immunoelectrophoresis, which demonstrated a monoclonal IgM spike, and a bone marrow aspirate that revealed lymphoplasmacytic lymphoma with extensive plasmacytic differentiation. The volume percentage of quantitative cryoglobulins was 1% (reference range, 0%-0.5%). He reported a history of peripheral neuropathy.
Bernstein LE, Shea CR, Baron JM. Erythematous Papules on the Legs—Quiz Case. Arch Dermatol. 2009;145(1):77-82. doi:10.1001/archdermatol.2008.556-a