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January 2009

Acral Atrophic Papules, Petechia, and Patches of Alopecia—Diagnosis

Author Affiliations
 

MICHAEL E.MINGMD

 

CARRIE ANN R.CUSACKMDSENAIT W.DYSONMDJACQUELINE M.JUNKINS-HOPKINSMDVINCENTLIUMDKARLA S.ROSENMANMD

Arch Dermatol. 2009;145(1):77-82. doi:10.1001/archdermatol.2008.557-b

Histopathologic examination of the biopsy specimens revealed a slightly acanthotic epidermis, with reticular fibroplasia of the papillary dermis. Intermediate-size lymphocytes with atypia were seen focally along the dermoepidermal junction. The eccrine coils were densely infiltrated with intermediate-size lymphocytes. Immunohistochemical analysis showed a CD4:CD8 ratio of greater than 10:1, and T-cell receptor gene rearrangement studies showed a positive T-cell clone. The diagnosis of syringotropic MF was made.

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