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January 2009

Asymptomatic, Edematous Upper Lip in a 39-Year-Old Woman—Diagnosis

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Copyright 2009 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2009

Arch Dermatol. 2009;145(1):77-82. doi:10.1001/archdermatol.2008.558-b

The biopsy findings demonstrated numerous, focally granulomatous infiltrates in the middermis, deep dermis, and at the level of some skeletal muscle bundles. Granulomata were predominately composed of epithelioid histiocytes. Dilated blood vessels and a loose lymphohistiocytic infiltrate were present in the upper dermis. Results from polarization microscopy failed to demonstrate the presence of foreign material. Results from periodic acid–Schiff reaction and acid-fast stains were negative. Erythrocyte sedimentation rate was elevated, and True Test findings (Allerderm, Phoenix, Arizona) demonstrated 1+ sensitivity to cobalt. Laboratory values for complete blood cell count, angiotensin-converting enzyme, and glucose-6-phosphate dehydrogenase level were within reference range.

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