I read with interest the article by Dompmartin and colleagues.1 A number of participants in the study were women of reproductive age. I was wondering if an important factor elevating D-dimer level was considered: the oral contraceptive pill, a widely prescribed drug, could contribute to such an event.2,3 Failure to be aware of this would lead to an incorrect incidence of high D-dimer levels.
Kittisupamongkol W. Oral Contraceptive and D-Dimer Level. Arch Dermatol. 2009;145(2):210. doi:10.1001/archdermatol.2008.565