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March 2009

Mount Tsukuba and the Origin of Tacrolimus

Arch Dermatol. 2009;145(3):284. doi:10.1001/archdermatol.2009.11

The historic, sacred mountain of Mount Tsukuba is situated approximately 60 km northeast of Tokyo in the central-eastern region of the Japanese archipelago. Rising 877 m above sea level, it comprises 2 distinct peaks: Nantai-san on the western side and Nyotai-san on the eastern side, both of which overlook the vast expanse of the Kanto plain. Part of the Tsukuba Quasi-National Park, Mount Tsukuba is a unique home to both cool and warm temperate plant communities, including deciduous and evergreen forests of Japanese beech, mizunara, and red oak, as well as 65 species of ferns.1 Several plants, including Tsukuba-kinmonso (Ajuga yesoensis var tsukubana) and Tsukuba-torikabuto (Aconitum japonicum ssp maritimum), were first discovered there.1

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