An 83-year-old white man was referred with multiple nodules on the scalp that had appeared 3 months earlier. The nodules were growing rapidly.
He had painless, erythematous, dome-shaped nodules on the scalp. The nodules ranged from 4 × 4 to 10 × 15 mm in diameter (Figure 1). An incisional biopsy specimen revealed small and round cells disposed in a trabecular pattern. Immunohistochemical analysis revealed strong positivity for cytokeratin 20 and neurofilament. On the basis of the histopathologic and immunohistochemical features, Merkel cell carcinoma (MCC) was diagnosed.
Curatolo P, Mancini M, Clerico R, Ruggiero A, Frascione P, Di Marco P, Frasca M, Calvieri S. Remission of Extensive Merkel Cell Carcinoma After Electrochemotherapy. Arch Dermatol. 2009;145(4):494-495. doi:10.1001/archdermatol.2009.25