May 2009

Remote Hemorrhagic Bullae Occurring in a Patient Treated With Subcutaneous Heparin

Author Affiliations

Copyright 2009 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2009

Arch Dermatol. 2009;145(5):604-605. doi:10.1001/archdermatol.2009.70

Hemorrhagic bullae often have underlying infectious causes. However, recent reports have suggested that they may also occur at sites distant from subcutaneous heparin injections,1,2 which have been linked to a variety of other skin manifestations including urticaria, erythema, calcinosis cutis, skin necrosis often secondary to vasculitis, and heparin-induced thrombocytopenia.3,4

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