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A 36-year-old woman presented with a painful and pruritic eruption on both feet. She had a history of asthma, allergic rhinitis, and chronic sinusitis and had been treated at various times with fexofenadine hydrochloride, mometasone furoate nasal spray, hydroxyzine hydrochloride, diphenhydramine hydrochloride, albuterol sulfate, montelukast sodium, fluticasone propionate, and salmeterol inhalation powder. She reported intermittent episodes of unilateral lower leg edema associated with pruritus, which had been treated with diphenhydramine in the past.
Farley-Loftus R, Anandasabapathy N, Bossenbroek N, Rosenman K, Pomeranz MK. An Unusual Pruritic Eruption of the Feet—Quiz Case. Arch Dermatol. 2009;145(6):715-720. doi:10.1001/archdermatol.2009.108-a