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August 2009

Pregnancy-Associated Dermatomyositis

Arch Dermatol. 2009;145(8):952-953. doi:10.1001/archdermatol.2009.159

Dermatomyositis (DM) is a female-predominant idiopathic inflammatory myopathy with characteristic skin manifestations. Reports of the association between DM and pregnancy are rare, although 2 types of pregnancy-related DM have been proposed: one presenting during pregnancy and the other, less common, developing post partum.1 Three case reports of the less common DM describe women who manifested symptoms of classic DM (CDM) 5, 15, and 30 days, respectively, after normal deliveries.13 In addition, postpartum exacerbation was reported 3 months after delivery and during the period following a spontaneous abortion.3,4 Various triggers for pregnancy-associated DM may include exposure of the mother to fetal antigens and maternal hormonal changes.1 We describe herein a patient who developed amyopathic DM (ADM) after a spontaneous abortion, which progressed 2 years later, following the delivery of a healthy infant, to CDM.

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