The notion that emotions may be associated with the development and progression of cancer is not new; indeed, this assumption was held for many centuries1 with scant scientific data to support it. During recent decades, numerous clinical and basic laboratory studies have provided evidence in support of the concept that biopsychosocial factors can influence malignant disease in animal models as well as in humans. The relevance of these investigations lies in the possibility of developing therapeutic strategies for patients with cancer that rely on psychological as well as psychoneuro-immunological principles in addition to traditional chemotherapeutic, radiation, and immunologically based treatments.
Smith N, Fuhrmann T, Tausk F. Psychoneuro-oncologyIts Time Has Arrived. Arch Dermatol. 2009;145(12):1439-1442. doi:10.1001/archdermatol.2009.306