Facial malignant staphylococcal infection is a rare infectious disorder characterized by a septic facial venous thrombosis. Herein we report the first case to our knowledge in a healthy young woman due to Panton-Valentine leukocidin (PVL)–positive Staphylococcus aureus.
A 20-year-old woman with no medical history was admitted for facial edema with high fever. She had been treated with amoxicillin plus clavulanic acid for 48 hours without efficacy. For a few days prior to presentation, she had a handled intranasal pock. Physical examination revealed significant inflammatory facial edema with periorbital predominance (Figure 1) and bilateral cervical adenopathies. Neurological and ophthalmological findings were normal.
Kramkimel N, Sbidian E, Duong TA, Lesprit P, Roujeau J, Bagot M. Septic Facial Vein Thrombosis Due to Panton-Valentine Leukocidin–Positive Staphylococcus aureus. Arch Dermatol. 2009;145(12):1460-1461. doi:10.1001/archdermatol.2009.317