December 2009

Septic Facial Vein Thrombosis Due to Panton-Valentine Leukocidin–Positive Staphylococcus aureus

Author Affiliations

Copyright 2009 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2009

Arch Dermatol. 2009;145(12):1460-1461. doi:10.1001/archdermatol.2009.317

Facial malignant staphylococcal infection is a rare infectious disorder characterized by a septic facial venous thrombosis. Herein we report the first case to our knowledge in a healthy young woman due to Panton-Valentine leukocidin (PVL)–positive Staphylococcus aureus.

A 20-year-old woman with no medical history was admitted for facial edema with high fever. She had been treated with amoxicillin plus clavulanic acid for 48 hours without efficacy. For a few days prior to presentation, she had a handled intranasal pock. Physical examination revealed significant inflammatory facial edema with periorbital predominance (Figure 1) and bilateral cervical adenopathies. Neurological and ophthalmological findings were normal.

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