Copyright 2001 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2001
Clark nevi (atypical melanocytic nevi) are commonly observed in dermatologic practice. The dermoscopic features of Clark nevi have not previously been described. This month in the ARCHIVES, Hofmann-Wellenhof et al present an easily applicable and reproducible dermoscopic classification scheme for these nevi.
Reticular-homogeneous type of Clark nevus. Scale bar indicates 1 mm.
Congenital hemangiomas differ from classic infantile hemangiomas in being fully formed at birth and even occasionally diagnosed in utero. These congenitally fully developed hemangiomas have previously been assumed to be simple variants of the more typical postnatally developing hemangiomas. North et al demonstrate distinct histopathologic and immunohistochemical findings in congenital hemangiomas, suggesting that the pathogenesis of these tumors differs from that of classically presenting hemangiomas of infancy.
Early diagnosis of melanoma is essential to the early institution of appropriate therapy. Digital dermatoscopy systems have recently become available that allow close monitoring of atypical melanocytic skin lesions over time. Kittler and Binder compare the usefulness of sequential imaging of these lesions with standard decision making in patients with multiple atypical nevi. In the hands of experienced users, sequential imaging of atypical melanocytic lesions increases diagnostic sensitivity and specificity.
The retinoid tretinoin has demonstrated benefit in photoaging treatment; tazarotene displays different nuclear retinoid receptor selectivity than tretinoin. Kang et al nonetheless demonstrate that tazarotene cream significantly improves the clinical and histologic appearance of photoaged skin.
Localized unilateral hyperhidrosis is a rare idiopathic disorder typically characterized by excessive sweating on the forearm or forehead without clear precipitant. Kreyden et al report the successful use of botulinum toxin A for treatment of this disorder.
This Month in Archives of Dermatology. Arch Dermatol. 2001;137(12):1565. doi:10.1001/archderm.137.12.1565