A “lupus band” of granular depositions of IgG and complement has been observed along the epidermal basement membrane zone in rare cases of pemphigus foliaceus. Using case reports, Oktarina and coauthors elucidate features of this variant of pemphigus foliaceus.
Handler and coauthors discuss the case of a married couple who had been using human growth hormone and who both were diagnosed as having melanoma within a short time span.
Haenssle and coauthors present the case of a patient with dynamic changes of melanocytic nevi well documented by sequential digital dermoscopy during vemurafenib therapy.
Wilkerson et al report the case of a 66-year-old woman who developed an exacerbation of subacute cutaneous lupus erythematosus (SCLE) 2 to 3 weeks after subcutaneous injection of golimumab for the treatment of rheumatoid arthritis. She had developed SCLE 2 years previously due to furosemide use and 10 years previously due to hydrochlorothiazide use.
In rare cases, autosomal recessive congenital ichthyosis can evolve into bathing suit ichthyosis and self-improving collodion ichthyosis. Bourrat et al speculated that a restricted spectrum of TGM1 mutations is susceptible to these phenotypes.
Wu and colleagues reviewed the records of 140 patients with granuloma annulare vs 420 controls to estimate the prevalence of dyslipidemia in this granulomatous skin disease.
Kasparian and colleagues examine the frequency and correlates of skin examination behaviors in an international sample of individuals at varying risk of developing melanoma.
To investigate whether Spitz nevi with typical histopathological features in 25 patients 50 years or older demonstrated chromosomal aberrations by 4-color FISH, Horst and colleagues performed a retrospective medical record review, with prospective masked histopathological and cytogenetic analyses.
To validate dermoscopy as a real-time noninvasive diagnostic imaging technique for actinic keratosis, Huerta-Brogeras and colleagues performed a prospective study among 178 patients with a clinical diagnosis of the lesions who underwent both dermoscopy and histopathological testing.
Leger and colleagues studied the prognostic factors for overall survival in a series of patients with paraneoplastic pemphigus using univariate and multivariate analyses.