Author Affiliations: Departments of Otolaryngology–Head and Neck Surgery and Plastic Surgery, Boston University School of Medicine, Boston, Mass.
Correspondence: Jeffrey H. Spiegel, MD, Departments of Otolaryngology–@Head and Neck Surgery and Plastic Surgery, Boston University School of Medicine, 88 E Newton St, Suite D-616, Boston, MA 02446 (Jeffrey.Spiegel@bmc.org).
Botulinum toxin type A is widely used for treatment of facial rhytids, often in an “off-label” fashion. Important mechanisms of action and safety concerns for such treatments are presented along with recommendations for treatment of periorbital rhytids.
Spiegel JH. Treatment of Periorbital Rhytids With Botulinum Toxin Type AMaximizing Safety and Results. Arch Facial Plast Surg. 2005;7(3):198-202. doi:10.1001/archfaci.7.3.198