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Invited Commentary
Aug 8 2011

Prevention of Type 2 DiabetesComment on “Lifestyle Modification and Prevention of Type 2 Diabetes in Overweight Japanese With Impaired Fasting Glucose Levels”

Author Affiliations

Author Affiliation: Diabetes Epidemiology and Clinical Research Section, National Institute of Diabetes and Digestive and Kidney Diseases, Phoenix, Arizona.

Arch Intern Med. 2011;171(15):1361-1362. doi:10.1001/archinternmed.2011.367

Prevention of type 2 diabetes mellitus (T2DM) has been studied in several randomized clinical trials16 in adults at high risk of developing diabetes. Most enrolled only persons with impaired glucose tolerance (IGT) during an oral glucose tolerance test (OGTT). Other high-risk characteristics often included obesity and elevated fasting plasma glucose (FPG) level. All these studies had OGTT-diagnosed diabetes as the primary outcome, although exact definitions differed among studies.

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